分子細胞修飾学 斉藤研究室 Molecular and Cellular Modification Saitoh LABORATORY

平成30年度 (2018年4月〜2019年3月)

スケジュール

03/27 お花見BBQ+柳井さん送別会 at 白川河川敷BBQ party for cherry blossom viewing + Farewell for Mr. Roy Yanai at Shirakawa-riverside area

4月

04/02 ミーティング+掃除Lab meeting & Clean-up Gulevin、高鉾、小林、宮崎,深井
04/04 10:00-10:30 熊本大学および大学院入学式at 県立劇場 Entrance Ceremony at KENRITU Ceremony Hall
04/06 学部・院生履修ガイダンス Class Room Guidance for new students
04/09 JC #1 JJ斉藤+Lab meeting & Clean-up
Phase separation of a yeast prion protein promotes cellular fitness. Franzmann TM, Jahnel M, Pozniakovsky A, Mahamid J, Holehouse AS, Nuske E, Richter D, Baumeister W, Grill SW, Pappu RV, Hyman AA, Alberti S. Science. 2018 Jan 5;359(6371). pii: eaao5654. doi: 10.1126/science.aao5654.
04/16 JC #2 Yui 高鉾+Lab meeting & Clean-up
Cytoplasmic chromatin triggers inflammation in senescence and cancer. Dou Z, Ghosh K, Vizioli MG, Zhu J, Sen P, Wangensteen KJ, Simithy J, Lan Y, Lin Y, Zhou Z, Capell BC, Xu C, Xu M, Kieckhaefer JE, Jiang T, Shoshkes-Carmel M, Tanim KMAA, Barber GN, Seykora JT, Millar SE, Kaestner KH, Garcia BA, Adams PD, Berger SL. Nature. 2017 Oct 19;550(7676):402-406. doi: 10.1038/nature24050. Epub 2017 Oct 4.
04/23 18:00〜3年生歓迎会 at くすのき会館
04/16 Lab Kickoff SymposiumキックオフシンポPR2 (including Experimental Plan for 2018)+Lab meeting and Clean-up
(04/30 *JCはお休み We have no JC on 04/30)

*04/29-05/06 `Golden Week` 〜National Spring Holiday〜

5月

05/07 JC #3 Momo 小林+Lab meeting & Clean-up
Amyloid domains in the cell nucleus controlled by nucleoskeletal protein lamin B1 reveal a new pathway of mercury neurotoxicity. Arnhold F, Guhrs KH, von Mikecz A. PeerJ. 2015 Feb 5;3:e754. doi: 10.7717/peerj.754. eCollection 2015.
05/08-10 学生実習(3年生) 1st week of the experimental training course for 3rd grade students
05/14 JC #4 Toki 徳永+Lab meeting & Clean-up
Natural noncanonical protein splicing yields products with diverse β-amino acid residues. Morinaka BI, Lakis E, Verest M, Helf MJ, Scalvenzi T, Vagstad AL, Sims J, Sunagawa S, Gugger M, Piel J. Science. 2018 Feb 16;359(6377):779-782. doi: 10.1126/science.aao0157.
05/15-17 学生実習(3年生) 2nd week of the experimental training course for 3rd grade students
05/21 JC #3 Zaki 宮崎+Lab meeting & Clean-up
Identification of seipin-linked factors that act as determinants of a lipid droplet subpopulation. Eisenberg-Bord M, Mari M, Weill U, Rosenfeld-Gur E, Moldavski O, Castro IG, Soni KG, Harpaz N, Levine TP, Futerman AH, Reggiori F, Bankaitis VA, Schuldiner M, Bohnert M. J Cell Biol. 2018 Jan 2;217(1):269-282. doi: 10.1083/jcb.201704122.
05/28  PR2+Lab meeting & Clean-up:Gizem-Gulevin、高鉾、岡田、小林、宮崎、深井

6月

06/04 JC #4 Saya 岡田+Lab meeting & Clean-up
Visualization of Membrane Pore in Live Cells Reveals a Dynamic-Pore Theory Governing Fusion and Endocytosis. Shin W, Ge L, Arpino G, Villarreal SA, Hamid E, Liu H, Zhao WD, Wen PJ, Chiang HC, Wu LG. Cell. 2018 May 3;173(4):934-945.e12. doi: 10.1016/j.cell.2018.02.062.
06/11 JC #5 Huki 深井+Lab meeting & Clean-up
Lysozyme Counteracts β-Lactam Antibiotics by Promoting the Emergence of L-Form Bacteria. Kawai Y, Mickiewicz K, Errington J. Cell. 2018 Feb 22;172(5):1038-1049.e10. doi: 10.1016/j.cell.2018.01.021.

06/18 JC #6 Gizem-Gulevin Takir+Lab meeting & Clean-up
     Loss of HSulf-1: The Missing Link between Autophagy and Lipid Droplets in Ovarian Cancer. Roy D, Mondal S,
     Khurana A, Jung DB, Hoffmann R,
     He X, Kalogera E, Dierks T, Hammond
     E, Dredge K, Shridhar V. Sci Rep. 2017
     Feb 7;7:41977. doi: 10.1038/srep41977.

06/25 10:00 飯星さん卒業証書の授与式
     at 生物会議室 Graduation ceremony
     10:30〜 Ii’s informal seminar
     “*Informal Seminar on Studies in the
     USA” +Lab meeting & Clean-up by Ii.
     12:00〜 Lunch with Ii

7月

07/02  PR2+Lab meeting & Clean-up
07/09 JC #8 JJ斉藤+Lab meeting & Clean-up Surface Properties Determining Passage Rates of Proteins through Nuclear Pores. Frey S, Rees R, Schunemann J, Ng SC, Funfgeld K, Huyton T, Gorlich D. Cell. 2018 Jun 28;174(1):202-217.e9. doi: 10.1016/j.cell.2018.05.045.
07/16 National Holiday *JCはお休みWe have no JC on 07/16
07/17 Lab meeting and Clean-up (starts at 10:00 am〜)
07/18-23 大学院願書受付 application period for the
       graduate school entrance
07/26  PR2+Lab meeting & Clean-up + TAKOYAKI and Beer Party at C216
07/02-07/31 分子生物学会(11/28-30 at Yokohama)の演題投稿締め切り Dead line of presentation acceptance for the
          the Meeting at Yokohama on Nov 28-30.

*8月〜9月夏休み August 〜 September: Summer Holiday, 2018; no JC, no lab meeting

8月

08/04 Open Campus⇒many high-school students will visit the university

08/13-14: all of the administration office in the university are closed.

08/23-24 Entrance examination for the graduate school

08/27 研究室旅行(人吉、球磨川ラフティング)

9月

09/06 JASSO短期留学生のプレゼンテーションと修了式(13:00〜 D棟B会議室)
16:00〜 Farwell Party for Gulevin and Ezgi at C216
09/09  PR2+Lab meeting & Clean-up

10月

*We will start JC and Lab meeting again. JC担当者の予定を決めておくといいでしょう。Please check JC schedule and determine the candidates for the presentations, respectively.
10/01 9:30〜 JC#1 by Saitoh+Lab meeting & Clean-up
The Inner Nuclear Membrane Is a Metabolically Active Territory that Generates Nuclear Lipid Droplets. Romanauska A, Kohler A. Cell. 2018 Jul 26;174(3):700-715.e18.
doi: 10.1016/j.cell.2018.05.047. Epub 2018 Jun 21. PMID:29937227
10/08 holiday (no JC)
10/09 lab meeting & Clean-up
10/15 9:30〜 JC#2 Yui高鉾+Lab meeting & Clean-up
C9orf72 nucleotide repeat structures initiate molecular cascades of disease. Haeusler AR, Donnelly CJ, Periz G, Simko EA, Shaw PG, Kim MS, Maragakis NJ, Troncoso JC, Pandey A, Sattler R, Rothstein JD, Wang J. Nature. 2014 Mar 13;507(7491):195-200. doi: 10.1038/nature13124. Epub 2014 Mar 5. PMID:24598541
10/22 9:30〜 JC#3 momo小林⇒延期(1/07)+Lab meeting & Clean-up
Adaptation to Stressors by Systemic Protein Amyloidogenesis. Audas TE, Audas DE, Jacob MD, Ho JJ, Khacho M, Wang M, Perera JK, Gardiner C, Bennett CA, Head T, Kryvenko ON, Jorda M, Daunert S, Malhotra A, Trinkle-Mulcahy L, Gonzalgo ML, Lee S. Dev Cell. 2016 Oct 24;39(2):155-168. doi: 10.1016/j.devcel.2016.09.002. Epub 2016 Oct 6. PMID:27720612
10/24  9:30〜 PR2+Lab meeting & Clean-up
10/26 1限目:3年生のための研究室紹介(斉藤が担当します)
 10/28-11/01 ベトナム・ハノイ周辺の高校へ出前授業(斉藤)

11月

11/5 JC#4 9:30〜 saya岡田+Lab meeting & Clean-up
A novel mechanism of generating extracellular vesicles during apoptosis via a beads-on-a-string membrane structure. Atkin-Smith GK, Tixeira R, Paone S, Mathivanan S, Collins C, Liem M, Goodall KJ, Ravichandran KS, Hulett MD, Poon IK. Nat Commun. 2015 Jun 15;6:7439. doi: 10.1038/ncomms8439. PMID:26074490
11/12 JC#5 9:30〜 Hucky深井+Lab meeting & Clean-up
Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response. Chen G, Huang AC, Zhang W, Zhang G, Wu M, Xu W, Yu Z, Yang J, Wang B, Sun H, Xia H, Man Q, Zhong W, Antelo LF, Wu B, Xiong X, Liu X, Guan L, Li T, Liu S, Yang R, Lu Y, Dong L, McGettigan S, Somasundaram R, Radhakrishnan R, Mills G, Lu Y, Kim J, Chen YH, Dong H, Zhao Y, Karakousis GC, Mitchell TC, Schuchter LM, Herlyn M, Wherry EJ, Xu X, Guo W. Nature. 2018 Aug;560(7718):382-386. doi: 10.1038/s41586-018-0392-8. Epub 2018 Aug 8.
11/19 JC#6 9:30〜 Tocky徳永+Lab meeting & Clean-up
In Situ Architecture and Cellular Interactions of PolyQ Inclusions. Bauerlein FJB, Saha I, Mishra A, Kalemanov M, Martinez-Sanchez A, Klein R, Dudanova I, Hipp MS, Hartl FU, Baumeister W, Fernandez-Busnadiego R. Cell. 2017 Sep 21;171(1):179-187.e10. doi: 10.1016/j.cell.2017.08.009. Epub 2017 Sep 7.
11/26  PR2(ポスター発表の方はその予行を、口頭発表の方はその予行をお願いします)
11/28-30 第41回日本分子生物学会(パシフィコ横浜)
*高鉾さんが1日目、岡田さんが3日目にワークショップで口頭発表。
2018年11月28日(水)

[1P-0211] アミロイド検出試薬を用いたSUMO・ユビキチン陽性の核内ポリペプチド鎖凝集体の検出とその制御解析
 〇小林 桃子1、斉藤 寿仁1,2 (1.熊大・理・生物、2.熊大
 ・先端科学・生物科学)

[1P-0209(1AW-06-5)] アミロイド結合性蛍光色素Thioflavin T(ThT)による生細胞の構造観察と細胞増殖の制御
 〇高鉾 結衣1、斉藤 寿仁1,2 (1.熊大・院・自然科学・生
 物、2.熊大・先端科学・生物)

[1P-0210] 微小管阻害による微小核の形成と脂肪滴の誘導
 〇宮ア 航平1、Gizem Gulevin Takir2、斉藤 寿仁1,2,3
  (1.熊大・理・生物、2.熊大・院・自然科学・生物、3.熊
 大・先端科学・生物科学)

2018年11月28日(水) 10:00 〜 10:10

[1AW-06-5(1P-0209)] アミロイド結合性蛍光色素Thioflavin T(ThT)による生細胞の構造観察と細胞増殖の制御
 〇高鉾 結衣1、斉藤 寿仁1,2 (1.熊大・院・自然科学・生物、2.熊大・先端科学・生物)

2018年11月29日(木)

[2P-0317(3AW-08-2)] 直径5-30μmの大型細胞膜小胞の効率的な単離および膜動態の操作
 〇岡田 咲耶1、斉藤 寿仁1,2 (1.熊大・院・自然科学・生物、2.熊大・先端科学・生物)

2018年11月30日(金) 09:22 〜 09:34

[3AW-08-2(2P-0317)] 直径5-30μmの大型細胞膜小胞の効率的な単離および膜動態の操作
 〇岡田 咲耶1、斉藤 寿仁1,2 (1.熊大・院・自然科学・生物、2.熊大・先端科学・生物)
*11/27新メンバー配属決定(5名)→12月から研究室で活動開始。New members will be distributed officially to the lab at the end of November 2018, and will start to join the Lab activities from December 2018.

12月

1月

2月

3月